Safety – It should be noted that NB-UVB is safer for the skin than sunlight. Sunlight contains the UVA rays which penetrate the skin more deeply than the UVB rays. Recently, scientists have learned that UVA rays while not contributing to sunburns, damage deeper layers of the skin and probably play an important role in wrinkling, spotting, lost elasticity and the dangerous skin cancer melanoma. UVB are the burning rays. By using Narrow Band-UVB you can achieve a therapeutic level of treatment in just a few minutes as opposed to the longer times required by sunlight, reducing your overall exposure to these potentially damaging rays.


Some say it’s underutilized or eclipsed by biologics, but it remains effective
~ By Jan Bowers, contributing writer, August 01, 2012


Phototherapy, used to treat psoriasis for the past 100 years, is a modality with proven efficacy and an excellent safety profile.

Dr. Koo emphasized the efficacy and safety of phototherapy as the strongest arguments in its favor. “There’s a misconception that phototherapy doesn’t work as well as biologics do,” he said. “Biologics are not the most effective therapy. In the entire medical literature worldwide, there are only two treatments where 100 percent of the patients achieved a 75 percent improvement or better (i.e., PASI 75) in their Psoriasis Area Severity Index score after 12 weeks, and both of those treatments are phototherapies, RePUVA and Goeckerman therapies (Expert Opinions in Pharmacotherapy 2007;8(5):617-32).”


Phototherapy in the Age of Biologics
~ Daniel Walker, BS, and Heidi Jacobe, MD, MSCS


Phototherapy represents an excellent option in several therapeutically challenging disorders by providing effective therapy without systemic side effects. Although most commonly associated with the treatments of psoriasis, phototherapy is a valuable tool in the treatment of a large number of skin disorders, many of which are disabling or have significant impact on life quality. This makes phototherapy relevant to modern dermatologic practice, even in the age of biological therapy. Further, the advent of more sophisticated devices using limited UV wavelengths or delivering targeted phototherapy continues to expand the role of this modality. 2011


Phototherapy with Narrowband UVB
Mark BERNEBURG, Martin RO¨ CKEN and Frauke BENEDIX
Department of Dermatology, Eberhard Karls University, Tuebingen, Germany


Phototherapy with ultraviolet (UV) radiation of wavelengths between 280 and 320 nm (UVB) is a safe and effective treatment for a variety of diseases. In addition to standard broadband UVB (bUVB), narrowband phototherapy with fluorescent bulbs emitting near monochromatic UV around 311 nm (nUVB) has become an important treatment for diseases such as psoriasis, atopic dermatitis and vitiligo. In addition to these indications, the number of diseases for which nUVB phototherapy is reported to be effective is continuously growing. The differential effects of nUVB phototherapy in comparison to other UV wavelengths as well as established and new indications for this treatment modality are reviewed.


(Accepted October 4, 2004) Acta Derm Venereol 2005; 85: 1–11.

Dr Mark Berneburg, Department of Dermatology, Eberhard Karls University, Liebermeisterstrasse 25, DE-72076 Tuebingen, Germany. E-mail: